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Caspase-3 Assay Kit (DCS3-100)

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Product details

Management number 220390883 Release Date 2026/05/03 List Price $123.60 Model Number 220390883
Category

Caspases are members of the aspartate-specific cysteinyl protease family that play a central role in apoptosis. Apoptosis is involved in a variety of physiological and pathological events, ranging from normal fetal development to diseases such as cancer, organ failure, and neurodegenerative diseases. Caspase-3 is key biomarker in the assessment of apoptosis and in understanding mechanism of apoptosis induction. BioAssay Systems’ Caspase-3 Assay Kit provides a convenient means to measure caspase-3 activity in biological samples. In the assay, a specific substrate (N-Ac-DEVD-AFC) is cleaved by active caspase-3, forming a highly fluorescent product. The fluorescence intensity (lexc/em = 400/490nm) is proportional to the caspase-3 activity. This product is for Research Use only and is not intended for diagnostic purposes.

  • Determination of the apoptosis target caspase-3 activity and HTS for apoptosis modulators.
  • Method: Fluorometric assay (400/490nm). A spectrophotometer or plate reader is required, but not provided.
  • Samples: Cell and tissue lysate. Species: All.
  • Procedure: 60 min. Size: 100 tests per kit
Item Weight 1 pounds
Manufacturer BioAssay Systems
Product Dimensions 5.5 x 4 x 2 inches
Is Discontinued By Manufacturer No

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